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SCOTT TYLER
Bench and computational biologist
This website is dedicated to my wet bench and computational biology projects - particularly those that are post-publication. If anyone would like to collaborate on any projects, has suggestions, or needs help with my research - feel free to get in touch!
Taking a data science approach to hypothesis generation and bench validation
PyMINEr
RESEARCH
From a single (brief) command line call, PyMINEr will perform the following informatics tasks:
unsupervised clustering
basic statistics & enrichment analyses
pathway analyses
Spearman correlation-based expression graphs that enable analyses by graph theory
creation of in silico predicted autocrine/paracrine signaling networks within and across cell types (if using scRNAseq)
creation of publication-ready visuals based on these analyses
generation of a web page explaining the results of the run
Future releases will contain updated clustering methods that work for reconstructing single cell lineages.